I have also been playing around with BLE, and decided to go with the Nordic nRF8001 chip because it looked easier to work with and didn’t require expensive IAR tools. nRF8001 is slightly cheaper than the CC2540 part in BLE112, but it is slave-only.
I bought Nordic’s nRF8001 development kit for $99, which includes nRF8001 samples and several nRF8001 boards (one with a trace antenna and one with an SMA connector) with standard 0.1" header for easy interfacing with your microcontroller development board. The documentation assumes that you have the $399 nRFgo development board and want to use the included nRF8200 microcontroller. I didn’t, so instead I wired an nRF8001 board directly to an Arduino.
You speak SPI to nRF8001, but basically with 2 different slave select-like pins. One pin (REQN) is a traditional slave select which is brought low to indicate that the master (you) want to send a message. The other pin (RDYN) is for the slave (nRF8001) to indicate that it received something over RF that it wants to send to the master, or that it is ready to receive a command from master. Master then brings REQN low and starts receiving.
The protocol is very concise and well documented (in the Product Specification PDF provided by Nordic) and I wrote an Arduino sketch to setup the nRF8001 and have it talking to my iPhone 4S in an afternoon. The format is basically one length byte, one command byte, and then optional command-specific arguments.
You will need Nordic’s nRFgo Studio software to create a configuration specifying the services your device will support; it will then include a services.h file containing the setup messages you need to send to nRF8001. I finally managed to emulate a heart rate monitor and display numbers in Nordic’s iOS demo app.
One big benefit of nRF8001 compared to BLE112 is that, apart from the proprietary setup messages generated by nRFgo Studio, you only deal with a well documented serial protocol. No firmware upgrades! It’s very cool that the CC2540 has an on-board 8051 microcontroller, but you’ll either need to pay thousands of dollars for the IAR tools or deal with the limitations and annoyances of BlueGiga’s software stack. A raw CC2540 is cheaper than nRF8001 plus a microcontroller, but BlueGiga’s boards are not cheap.
(There is a UART on the nRF8001 that is brought out on the boards included in the development kit, but it’s only for Bluetooth’s Direct Test Mode and isn’t ordinarily used.)
There isn't much information about the bluetooth/radio chip embedded in the newer iPhones (4s, 5, iPad 2, newer macs), but it is commonly known to be a Dual Mode Bluetooth 4.0. They can access older Bluetooth (v1.x) Bluetooth + EDR (v2.x) and Bluetooth + HS (v3.x) devices, as well as newer Bluetooth v4.0 AND BLE v4.0 devices.
The host chip on the iPhone can talk to both, but not at the same time. A BLE slave device can only talk to a BLE host. A BR/EDR device can only talk to a BR/EDR Host. There can be dual-mode slaves, but not really.
Yes, you can use your iPhone with Bluetooth v4 to talk to a basic BR/EDR device. You can't use a iPhone with BT v2.x to talk to a BLE device.
Best Answer
Got this answer from TI E2E forum.
As per the Bluetooth SPEC, mote with BLE 4.1 should be backward compatible with Bluetooth 4.0. But you should keep in mind that you will not be able to take advantage of BLE 4.1 features. Mote will be as good as an Bluetooth 4.0 device.
Again it also depends on whether the mote device wants to go ahead with a BLE Connection with an older device. Because even if the SPEC says that 4.1 device is backward compatible, it goes to the manufacturer to decide whether they want to go ahead with an backward device.