Creating an instance service file using an ansible template

You can utilize magic variables group_names and groups to look up groups defined in your inventory:

---
- hosts: webservers
  vars:
    dcs: [dc_1, dc_2, dc_3]
  tasks:
  - debug:
      msg: |
        upstream backend {
        {%- for dc in dcs %}
        {%-   if dc in group_names %}
        {%-     for host in groups[dc+'_appservers'] %}
        server {{host}};
        {%-     endfor %}
        {%-   endif %}
        {%- endfor %}
        }

This playbook will give you the following output.

TASK: [debug ]     **************************************************************** 
ok: [10.43.0.10] => {
    "msg": "upstream backend { server 10.43.0.20; server 10.43.0.21;}"
}
ok: [10.43.10.10] => {
    "msg": "upstream backend { server 10.43.10.20; server 10.43.10.21;}"
}
ok: [10.43.20.10] => {
    "msg": "upstream backend { server 10.43.20.20; server 10.43.20.21;}"
}

Change server {{host}}; as you need to.

Well, assuming that the only thing changing per unit file is the remote.example.com part, you can use an Instantiated Service.

From the systemd.unit man page:

Optionally, units may be instantiated from a template file at runtime. This allows creation of multiple units from a single configuration file. If systemd looks for a unit configuration file, it will first search for the literal unit name in the file system. If that yields no success and the unit name contains an "@" character, systemd will look for a unit template that shares the same name but with the instance string (i.e. the part between the "@" character and the suffix) removed. Example: if a service getty@tty3.service is requested and no file by that name is found, systemd will look for getty@.service and instantiate a service from that configuration file if it is found.

Basically, you create a single unit file, which contains a variable (usually %i) where the differences occur and then they get linked when you "enable" that service.

For example, I have a unit file called /etc/systemd/system/autossh@.service that looks like this:

[Unit]
Description=AutoSSH service for ServiceABC on %i
After=network.target

[Service]
Environment=AUTOSSH_GATETIME=30 AUTOSSH_LOGFILE=/var/log/autossh/%i.log AUTOSSH_PIDFILE=/var/run/autossh.%i.pid
PIDFile=/var/run/autossh.%i.pid
#Type=forking
ExecStart=/usr/bin/autossh -M 40000 -NR 5000:127.0.0.1:5000 -i /opt/ServiceABC/.ssh/id_rsa_ServiceABC -l ServiceABC %i

[Install]
WantedBy=multi-user.target

Which I've then enabled

[user@anotherhost ~]$ sudo systemctl enable autossh@somehost.example.com
ln -s '/etc/systemd/system/autossh@.service' '/etc/systemd/system/multi-user.target.wants/autossh@somehost.example.com.service'

And can intereact with

[user@anotherhost ~]$ sudo systemctl start autossh@somehost.example.com
[user@anotherhost ~]$ sudo systemctl status autossh@somehost.example.com
autossh@somehost.example.service - AutoSSH service for ServiceABC on somehost.example
   Loaded: loaded (/etc/systemd/system/autossh@.service; enabled)
   Active: active (running) since Tue 2015-10-20 13:19:01 EDT; 17s ago
 Main PID: 32524 (autossh)
   CGroup: /system.slice/system-autossh.slice/autossh@somehost.example.com.service
           ├─32524 /usr/bin/autossh -M 40000 -NR 5000:127.0.0.1:5000 -i /opt/ServiceABC/.ssh/id_rsa_ServiceABC -l ServiceABC somehost.example.com
           └─32525 /usr/bin/ssh -L 40000:127.0.0.1:40000 -R 40000:127.0.0.1:40001 -NR 5000:127.0.0.1:5000 -i /opt/ServiceABC/.ssh/id_rsa_ServiceABC -l ServiceABC somehost.example.com

Oct 20 13:19:01 anotherhost.example.com systemd[1]: Started AutoSSH service for ServiceABC on somehost.example.com.
[user@anotherhost ~]$ sudo systemctl status autossh@somehost.example.com
[user@anotherhost ~]$ sudo systemctl status autossh@somehost.example.com
autossh@somehost.example.com.service - AutoSSH service for ServiceABC on somehost.example.com
   Loaded: loaded (/etc/systemd/system/autossh@.service; enabled)
   Active: inactive (dead) since Tue 2015-10-20 13:24:10 EDT; 2s ago
  Process: 32524 ExecStart=/usr/bin/autossh -M 40000 -NR 5000:127.0.0.1:5000 -i /opt/ServiceABC/.ssh/id_rsa_ServiceABC -l ServiceABC %i (code=exited, status=0/SUCCESS)
 Main PID: 32524 (code=exited, status=0/SUCCESS)

Oct 20 13:19:01 anotherhost.example.com systemd[1]: Started AutoSSH service for ServiceABC on somehost.example.com.
Oct 20 13:24:10 anotherhost.example.com systemd[1]: Stopping AutoSSH service for ServiceABC on somehost.example.com...
Oct 20 13:24:10 anotherhost.example.com systemd[1]: Stopped AutoSSH service for ServiceABC on somehost.example.com.

As you can see, all instances of %i in the unit file get replaced with somehost.example.com.

There's a bunch more specifiers that you can use in a unit file though, but I find %i to work best in cases like this.