Mac OS X Network User account login with local admin password

It would be painful and tedious, but the next step I would pursue is running the application under dtruss (or ktrace if you're on an older OS X). This way you can see exactly which calls are failing.

Something like this should do the trick:

sudo dtruss -f open /Applications/Adobe Bridge CS3/Bridge CS3.app > dtruss.out 2>&1

Of course, that only works if the errors occur during startup. If they are triggered by activity once the application is already open, you'll need to identify the PID of the running app and run something like this:

sudo dtruss -f -p $PIDOFAPP > dtruss.out 2>&1

When analyzing the dtruss.out file, grep -v is your friend.

Did you bind the mac to an OSX Server or to Active Directory? If the latter check if the domain ends in .local. If it does there are some known problems with multicast interference on OSX. The process here may work for you: http://www.macwindows.com/TIP-Lion-dot-local-AD-disable-multicast.html

Some Macs just plain aren't happy on an AD network. I've had several iMacs with essentially identical specs and most were fine but 2 kept losing connectivity with the domain controller and had constant kerberos ticket related issues. In this case breaking the mac from the domain and then reconnecting it using Centrify Express resolved the issue. You can find the agent on their website here: http://www.centrify.com/express/free-active-directory-tools-for-linux-mac.asp#agents