Nginx – connect() failed (111: Connection refused) while connecting to upstream, client

I get this error message in my log :

*329 connect() failed (111: Connection refused) while connecting to upstream, client: 37.24.154.207, server: domain.de, request: "POST /wp-admin/admin-ajax.php HTTP/1.1", upstream: "fastcgi://127.0.0.1:9065", host: "domain.de", referrer: "http://domain.de/wp-admin/edit.php?post_status=draft&post_type=post"

I dont know why ?

My nginx config:

server {
        listen xx.xx.xx.xx:80;


        server_name domain.de www.domain.de;

        root   /var/www/domain.de/web;

        if ($http_host = "www.domain.de") {
            rewrite ^ $scheme://domain.de$request_uri? permanent;
        }


        index index.html index.htm index.php index.cgi index.pl index.xhtml;



        error_page 400 /error/400.html;
        error_page 401 /error/401.html;
        error_page 403 /error/403.html;
        error_page 404 /error/404.html;
        error_page 405 /error/405.html;
        error_page 500 /error/500.html;
        error_page 502 /error/502.html;
        error_page 503 /error/503.html;
        recursive_error_pages on;
        location = /error/400.html {

            internal;
        }
        location = /error/401.html {

            internal;
        }
        location = /error/403.html {

            internal;
        }
        location = /error/404.html {

            internal;
        }
        location = /error/405.html {

            internal;
        }
        location = /error/500.html {

            internal;
        }
        location = /error/502.html {

            internal;
        }
        location = /error/503.html {

            internal;
        }

        error_log /var/log/ispconfig/httpd/domain.de/error.log;
        access_log /var/log/ispconfig/httpd/domain.de/access.log combined;

        location ~ /\. {
            deny all;
            access_log off;
            log_not_found off;
        }

        location = /favicon.ico {
            log_not_found off;
            access_log off;
        }

        location = /robots.txt {
            allow all;
            log_not_found off;
            access_log off;
        }

        location /stats {

            index index.html index.php;
            auth_basic "Members Only";
            auth_basic_user_file /var/www/clients/clientx/webx/web/stats/.htpasswd_stats;
        }

        location ^~ /awstats-icon {
            alias /usr/share/awstats/icon;
        }

        location ~ \.php$ {
            try_files /42e542cd7d9a862ffdaefe4211xxxxx.htm @php;
        }

        location @php {
            try_files $uri =404;
            include /etc/nginx/fastcgi_params;
            fastcgi_pass 127.0.0.1:9065;
            fastcgi_index index.php;
            fastcgi_param SCRIPT_FILENAME $document_root$fastcgi_script_name;
            fastcgi_intercept_errors on;
        }





        client_max_body_size 100M;

        location / {
                        try_files $uri $uri/ /index.php?$args;
        }

        rewrite /wp-admin$ $scheme://$host$uri/ permanent;

        location ~* \.(jpg|jpeg|png|gif|css|js|ico)$ {
                        expires max;
                        log_not_found off;
        }

                gzip_static on;
                set $supercacheuri "";
                set $supercachefile "$document_root/wp-content/cache/supercache/${http_host}${uri}index.html";
                if (-e $supercachefile) {
                    set $supercacheuri "/wp-content/cache/supercache/${http_host}${uri}index.html";
                }
                if ($request_method = POST) {
                    set $supercacheuri "";
                }
                if ($query_string) {
                    set $supercacheuri "";
                }
                if ($http_cookie ~* comment_author_|wordpress_logged_in|wp-postpass_) {
                    set $supercacheuri "";
                }
                if ($http_x_wap_profile) {
                    set $supercacheuri "";
                }
                if ($http_profile) {
                    set $supercacheuri "";
                }
                if ($http_user_agent ~* (2.0\ MMP|240x320|400X240|AvantGo|BlackBerry|Blazer|Cellphone|Danger|DoCoMo|Elaine/3.0|EudoraWeb|Googlebot-Mobile|hiptop|IEMobile|KYOCERA/WX310K|LG/U990|MIDP-2.|MMEF20|MOT-V|NetFront|Newt|Nintendo\ Wii|Nitro|Nokia|Opera\ Mini|Palm|PlayStation\ Portable|portalmmm|Proxinet|ProxiNet|SHARP-TQ-GX10|SHG-i900|Small|SonyEricsson|Symbian\ OS|SymbianOS|TS21i-10|UP.Browser|UP.Link|webOS|Windows\ CE|WinWAP|YahooSeeker/M1A1-R2D2|iPhone|iPod|Android|BlackBerry9530|LG-TU915\ Obigo|LGE\ VX|webOS|Nokia5800)) {
                    set $supercacheuri "";
                }
                if ($http_user_agent ~* (w3c\ |w3c-|acs-|alav|alca|amoi|audi|avan|benq|bird|blac|blaz|brew|cell|cldc|cmd-|dang|doco|eric|hipt|htc_|inno|ipaq|ipod|jigs|kddi|keji|leno|lg-c|lg-d|lg-g|lge-|lg/u|maui|maxo|midp|mits|mmef|mobi|mot-|moto|mwbp|nec-|newt|noki|palm|pana|pant|phil|play|port|prox|qwap|sage|sams|sany|sch-|sec-|send|seri|sgh-|shar|sie-|siem|smal|smar|sony|sph-|symb|t-mo|teli|tim-|tosh|tsm-|upg1|upsi|vk-v|voda|wap-|wapa|wapi|wapp|wapr|webc|winw|winw|xda\ |xda-)) {
                    set $supercacheuri "";
                }
                if ($supercacheuri) {
                    rewrite ^ $supercacheuri break;
                }


}