Server with 3 Disk, what’s the best HD Configuration

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I Have an HP Server with a quad core Opteron and 3 Disk 250Gb S-ATA Disk, i'm thinking about what's the best configuration of the disk for performance and reliability.

There is mainly 2 scenario :
-RAID 5 with these 3 HD (on the the array 100GB Partition for OS, Other Space for Data Partition)
-RAID 1 + 1 Disk for OS (one single Disk OS Installation, RAID 1 Array for a Data Partition)

What's the best configuration ?

In the Server Run MySQL and Small Document File server, the OS to be installed is Windows Server 2008 …

Best Answer

Best option is to buy a 4th disk and R10 them.