C# – Calculate difference between two dates (number of days)

string is an alias in C# for System.String.
So technically, there is no difference. It's like int vs. System.Int32.

As far as guidelines, it's generally recommended to use string any time you're referring to an object.

e.g.

string place = "world";

Likewise, I think it's generally recommended to use String if you need to refer specifically to the class.

e.g.

string greet = String.Format("Hello {0}!", place);

This is the style that Microsoft tends to use in their examples.

It appears that the guidance in this area may have changed, as StyleCop now enforces the use of the C# specific aliases.

If you have two date objects, you can just subtract them, which computes a timedelta object.

from datetime import date

d0 = date(2008, 8, 18)
d1 = date(2008, 9, 26)
delta = d1 - d0
print(delta.days)

The relevant section of the docs: https://docs.python.org/library/datetime.html.

See this answer for another example.