C# – DataGrid refresh after cell edit

If you have the row,column index of the cell/cells that you wish to have disabled:

int r = 2, c = 4;

Then you can listen to the events CellEnter and CellLeave and do the following:

    private void dataGridView1_CellEnter(object sender, DataGridViewCellEventArgs e)
    {
        if (e.RowIndex == r)
        {
            if (e.ColumnIndex == c)
            {
                dataGridView1.Columns[e.ColumnIndex].ReadOnly = true;
            }
        }
    }

    private void dataGridView1_CellLeave(object sender, DataGridViewCellEventArgs e)
    {
        if (e.RowIndex == r)
        {
            if (e.ColumnIndex == c)
            {
                dataGridView1.Columns[e.ColumnIndex].ReadOnly = false;
            }
        }
    }

You're still setting the entire column to Readonly, but since you are resetting it back after you leave the cell it has the effect of appearing to only work for the cell.

You can use UpdateSourceTrigger=PropertyChangedon the binding of the property member for the datagrid. This will ensure that when CellEditEnding is fired the update has already been reflected in the observable collection.

See below

<DataGrid SelectionMode="Single"
          AutoGenerateColumns="False"
          CanUserAddRows="False"
          ItemsSource="{Binding Path=Items}" // This is your ObservableCollection
          SelectedIndex="{Binding SelectedIndexStory}">
          <e:Interaction.Triggers>
              <e:EventTrigger EventName="CellEditEnding">
                 <cmd:EventToCommand PassEventArgsToCommand="True" Command="{Binding EditStoryCommand}"/> // Mvvm light relay command
               </e:EventTrigger>
          </e:Interaction.Triggers>
          <DataGrid.Columns>
                    <DataGridTextColumn Header="Description"
                        Binding="{Binding Name, UpdateSourceTrigger=PropertyChanged}" /> // Name is property on the object i.e Items.Name
          </DataGrid.Columns>

</DataGrid>

UpdateSourceTrigger = PropertyChanged will change the property source immediately whenever the target property changes.

This will allow you to capture edits to items as adding an event handler to the observable collection changed event does not fire for edits of objects in the collection.