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In C# 5 and earlier, to give auto implemented properties an initial value, you have to do it in a constructor.

Since C# 6.0, you can specify initial value in-line. The syntax is:

public int X { get; set; } = x; // C# 6 or higher

DefaultValueAttribute is intended to be used by the VS designer (or any other consumer) to specify a default value, not an initial value. (Even if in designed object, initial value is the default value).

At compile time DefaultValueAttribute will not impact the generated IL and it will not be read to initialize the property to that value (see DefaultValue attribute is not working with my Auto Property).

Example of attributes that impact the IL are ThreadStaticAttribute, CallerMemberNameAttribute, ...

The simplest way is an anonymous method passed into Label.Invoke:

// Running on the worker thread
string newText = "abc";
form.Label.Invoke((MethodInvoker)delegate {
    // Running on the UI thread
    form.Label.Text = newText;
});
// Back on the worker thread

Notice that Invoke blocks execution until it completes--this is synchronous code. The question doesn't ask about asynchronous code, but there is lots of content on Stack Overflow about writing asynchronous code when you want to learn about it.