Css – How to vertically center content with variable height within a div

2015 update: the flexbox approach

There are two other answers briefly mentioning flexbox; however, that was more than two years ago, and they don't provide any examples. The specification for flexbox has definitely settled now.

Note: Though CSS Flexible Boxes Layout specification is at the Candidate Recommendation stage, not all browsers have implemented it. WebKit implementation must be prefixed with -webkit-; Internet Explorer implements an old version of the spec, prefixed with -ms-; Opera 12.10 implements the latest version of the spec, unprefixed. See the compatibility table on each property for an up-to-date compatibility status.

(taken from https://developer.mozilla.org/en-US/docs/Web/Guide/CSS/Flexible_boxes)

All major browsers and IE11+ support Flexbox. For IE 10 or older, you can use the FlexieJS shim.

To check current support you can also see here: http://caniuse.com/#feat=flexbox

Working example

With flexbox you can easily switch between any of your rows or columns either having fixed dimensions, content-sized dimensions or remaining-space dimensions. In my example I have set the header to snap to its content (as per the OPs question), I've added a footer to show how to add a fixed-height region and then set the content area to fill up the remaining space.

html,
body {
  height: 100%;
  margin: 0;
}

.box {
  display: flex;
  flex-flow: column;
  height: 100%;
}

.box .row {
  border: 1px dotted grey;
}

.box .row.header {
  flex: 0 1 auto;
  /* The above is shorthand for:
  flex-grow: 0,
  flex-shrink: 1,
  flex-basis: auto
  */
}

.box .row.content {
  flex: 1 1 auto;
}

.box .row.footer {
  flex: 0 1 40px;
}

<!-- Obviously, you could use HTML5 tags like `header`, `footer` and `section` -->

<div class="box">
  <div class="row header">
    <p><b>header</b>
      <br />
      <br />(sized to content)</p>
  </div>
  <div class="row content">
    <p>
      <b>content</b>
      (fills remaining space)
    </p>
  </div>
  <div class="row footer">
    <p><b>footer</b> (fixed height)</p>
  </div>
</div>

In the CSS above, the flex property shorthands the flex-grow, flex-shrink, and flex-basis properties to establish the flexibility of the flex items. Mozilla has a good introduction to the flexible boxes model.

You can apply this CSS to the inner <div>:

#inner {
  width: 50%;
  margin: 0 auto;
}

Of course, you don't have to set the width to 50%. Any width less than the containing <div> will work. The margin: 0 auto is what does the actual centering.

If you are targeting Internet Explorer 8 (and later), it might be better to have this instead:

#inner {
  display: table;
  margin: 0 auto;
}

It will make the inner element center horizontally and it works without setting a specific width.

Working example here:

#inner {
  display: table;
  margin: 0 auto;
  border: 1px solid black;
}

#outer {
  border: 1px solid red;
  width:100%
}

<div id="outer">
  <div id="inner">Foo foo</div>
</div>

EDIT

With flexbox it is very easy to style the div horizontally and vertically centered.

#inner {  
  border: 1px solid black;
}

#outer {
  border: 1px solid red;
  width:100%;
  display: flex;
  justify-content: center;
}

<div id="outer">
  <div id="inner">Foo foo</div>
</div>

To align the div vertically centered, use the property align-items: center.