.net – Removing Oracle Data Provider for .NET from Global Assembly Cache

The PDBs for stepping through the source code are only posted for RTM and Service Packs. As such, when security update comes out and it modifies the dll you are trying to debug, it will cause source stepping to not work (that is, you'll get the "No source Available" with a greyed out "Browse to find Source").

However, once you've made all the appropriate settings, you can use the following workaround. The workaround is essentially to find the security updates that caused the dll to change, and then remove them. This has the obvious downside of having those security updates removed on your machine.

Workaround

1. Identify which dll you want to debug into (e.g. System.Windows.Forms.dll)
2. While debugging, open the Modules window in Visual studio, find the Version column. If the version is not the RTM or Service pack version, then you'll need to do the workflow. Typically the RTM dll will say "built by: RTMRel". While a dll that was part of a security update will say "built by: RTMGDR". Note the version number (for example 4.0.30319.269 built by: RTMGDR)
3. Now, we want to find the update that created this version. Do this by searching for the dll and version number at support.microsoft.com/kb/ For example, I did the following google search: site:support.microsoft.com/kb System.Windows.Forms.dll 4.0.30319.269
4. The search should turn up information about an update. Note the KB number in the address bar. In my example the address was http://support.microsoft.com/kb/2604121, so KB2604121, is what we're interested in.
5. Go to Control Panel->Programs and Features, and click "View Installed Updates"
6. Find an update which lists the KB number (you can use the search in the upper right box).
7. Uninstall that update.
8. Repeat this process for this same dll until the dll is back to its RTMRel version or SP version. For example, for System.Windows.Forms.dll, I had to remove KB2686827, KB2604121, KB2518870 before it was back to the RTMRel version.

You'll need to do this for each dll within the .NET framework that you care about debugging into.

Once that's done, set a breakpoint within the .net source (for example, go to the Breakpoints tab, say New->Break at Function, and enter System.Windows.Forms.Form.Form) or step into one of the .net methods in that dll.

I had the exact same problem.
The reason - bad IIS config file.

Try deleting the automatically-created IISExpress folder, which is usually located at %userprofile%/Documents, e.g. C:\Users\[you]\Documents\IISExpress.

Don't worry, VS should create it again - correctly, this time - once you run your solution again.

EDIT: Command line for deleting the folder:

rmdir /s /q "%userprofile%\Documents\IISExpress"