Qt – How to test labels in QTP

You could use descriptive programming to bypass the object map. QTP will ignore panel objects by default. You could try to get a reference to the panel object dynamically, then search the ChildObjects collection to find the ok button. Another option might be to simply add an ordinal identifier to the ok buttons.

• Button A: "Window Title/OK index #1"
• Button B: "Window Title/OK index #2"

This is an answer I wrote before, updated to your situation:

Can you see the BHOManager class in IE?

Go to IE > Tools > Manage Add-ons, make sure BHOManager class 
(Browser Helper Object) from Mercury Interative Corporation is 
enabled.   

It is recommended to disable other add-ons, such as third-party toolbar, add- ons from anti-virus companies, etc. This is to make sure nothing is preventing QTP from hooking into the browser.

If this is all the case, you re-register the BHOManager again:

Close IE and all iexplore.exe processes in the task manager
Close QTP (or restart your machine)
Go to Start > Run, unregister and register BHOManager.dll: 
    regsvr32 -u c:\WINDOWS\system32\BHOManager.dll 
    regsvr32 c:\WINDOWS\system32\BHOManager.dll 

When this solves your second run, you know there is something wrong with the BHO in IE: They are not started correctly or they are refused the second time. Maybe a more strict IT policy or an eager virus scanner that removes all not recognized browser add ins.