R dplyr: Drop multiple columns

You can use the order() function directly without resorting to add-on tools -- see this simpler answer which uses a trick right from the top of the example(order) code:

R> dd[with(dd, order(-z, b)), ]
    b x y z
4 Low C 9 2
2 Med D 3 1
1  Hi A 8 1
3  Hi A 9 1

Edit some 2+ years later: It was just asked how to do this by column index. The answer is to simply pass the desired sorting column(s) to the order() function:

R> dd[order(-dd[,4], dd[,1]), ]
    b x y z
4 Low C 9 2
2 Med D 3 1
1  Hi A 8 1
3  Hi A 9 1
R> 

rather than using the name of the column (and with() for easier/more direct access).

You can use a simple list of names :

DF <- data.frame(
  x=1:10,
  y=10:1,
  z=rep(5,10),
  a=11:20
)
drops <- c("x","z")
DF[ , !(names(DF) %in% drops)]

Or, alternatively, you can make a list of those to keep and refer to them by name :

keeps <- c("y", "a")
DF[keeps]

EDIT : For those still not acquainted with the drop argument of the indexing function, if you want to keep one column as a data frame, you do:

keeps <- "y"
DF[ , keeps, drop = FALSE]

drop=TRUE (or not mentioning it) will drop unnecessary dimensions, and hence return a vector with the values of column y.