R – Visual Studio Performance when editing XAML/Silverlight files

If you open the .aspx file and switch between design view and html view and back it will prompt VS to check the controls and add any that are missing to the designer file.

In VS2013-15 there is a Convert to Web Application command under the Project menu. Prior to VS2013 this option was available in the right-click context menu for as(c/p)x files. When this is done you should see that you now have a *.Designer.cs file available and your controls within the Design HTML will be available for your control.

PS: This should not be done in debug mode, as not everything is "recompiled" when debugging.

Some people have also reported success by (making a backup copy of your .designer.cs file and then) deleting the .designer.cs file. Re-create an empty file with the same name.

There are many comments to this answer that add tips on how best to re-create the designer.cs file.

These files contain user preference configurations that are in general specific to your machine, so it's better not to put it in SCM. Also, VS will change it almost every time you execute it, so it will always be marked by the SCM as 'changed'. I don't include either, I'm in a project using VS for 2 years and had no problems doing that. The only minor annoyance is that the debug parameters (execution path, deployment target, etc.) are stored in one of those files (don't know which), so if you have a standard for them you won't be able to 'publish' it via SCM for other developers to have the entire development environment 'ready to use'.