Temporary ASP.NET Files Missing

In my asp project throw error at the time running.

Yesterday it works nicely. But today morning it self it gives below message.

   Could not load file or assembly 'file:///C:\Windows\Microsoft.NET\Framework\v4.0.30319\Temporary ASP.NET Files\root\bd6e4bde\6cbdacc0\App_global.asax.j5j-uxp-.dll' or one of its dependencies. The system cannot find the file specified.

Pls Any one tell me why it happnens and how to solve this issue.

Full Error is

Assembly Load Trace: The following information can be helpful to
determine why the assembly
'file:///C:\Windows\Microsoft.NET\Framework\v4.0.30319\Temporary
ASP.NET Files\root\bd6e4bde\6cbdacc0\App_global.asax.j5j-uxp-.dll'
could not be loaded.

=== Pre-bind state information === LOG: User = HOME-PC\HOME LOG: Where-ref bind. Location =
C:\Windows\Microsoft.NET\Framework\v4.0.30319\Temporary ASP.NET
Files\root\bd6e4bde\6cbdacc0\App_global.asax.j5j-uxp-.dll LOG: Appbase
= file:///G:/Jagadeeswaran/Test Project/MobileApp/MobileApp/MobileApp/ LOG: Initial PrivatePath = G:\Jagadeeswaran\Test
Project\MobileApp\MobileApp\MobileApp\bin Calling assembly :
(Unknown).
=== LOG: This bind starts in LoadFrom load context. WRN: Native image will not be probed in LoadFrom context. Native image will only be
probed in default load context, like with Assembly.Load(). LOG: Using
application configuration file: G:\Jagadeeswaran\Test
Project\MobileApp\MobileApp\MobileApp\web.config LOG: Using host
configuration file: LOG: Using machine configuration file from
C:\Windows\Microsoft.NET\Framework\v4.0.30319\config\machine.config.
LOG: Attempting download of new URL
file:///C:/Windows/Microsoft.NET/Framework/v4.0.30319/Temporary
ASP.NET Files/root/bd6e4bde/6cbdacc0/App_global.asax.j5j-uxp-.dll.

Stack Trace:

[FileNotFoundException: Could not load file or assembly 'file:///C:\Windows\Microsoft.NET\Framework\v4.0.30319\Temporary

ASP.NET Files\root\bd6e4bde\6cbdacc0\App_global.asax.j5j-uxp-.dll' or
one of its dependencies. The system cannot find the file specified.]
System.Reflection.RuntimeAssembly._nLoad(AssemblyName fileName, String codeBase, Evidence assemblySecurity, RuntimeAssembly
locationHint, StackCrawlMark& stackMark, Boolean throwOnFileNotFound,
Boolean forIntrospection, Boolean suppressSecurityChecks) +0
System.Reflection.RuntimeAssembly.nLoad(AssemblyName fileName, String codeBase, Evidence assemblySecurity, RuntimeAssembly
locationHint, StackCrawlMark& stackMark, Boolean throwOnFileNotFound,
Boolean forIntrospection, Boolean suppressSecurityChecks) +39
System.Reflection.RuntimeAssembly.InternalLoadAssemblyName(AssemblyName
assemblyRef, Evidence assemblySecurity, StackCrawlMark& stackMark,
Boolean forIntrospection, Boolean suppressSecurityChecks) +132
System.Reflection.Assembly.Load(AssemblyName assemblyRef, Evidence assemblySecurity) +28
System.CodeDom.Compiler.CompilerResults.get_CompiledAssembly() +93
System.Web.Compilation.BuildProvider.CreateBuildResult(CompilerResults
results) +65
System.Web.Compilation.BuildProvider.GetBuildResult(CompilerResults
results) +16
System.Web.Compilation.ApplicationBuildProvider.GetGlobalAsaxBuildResult(Boolean
isPrecompiledApp) +8999743
System.Web.Compilation.BuildManager.CompileGlobalAsax() +50
System.Web.Compilation.BuildManager.EnsureTopLevelFilesCompiled() +265

[HttpException (0x80004005): Could not load file or assembly 'file:///C:\Windows\Microsoft.NET\Framework\v4.0.30319\Temporary

ASP.NET Files\root\bd6e4bde\6cbdacc0\App_global.asax.j5j-uxp-.dll' or
one of its dependencies. The system cannot find the file specified.]
System.Web.Compilation.BuildManager.ReportTopLevelCompilationException()
+62
System.Web.Compilation.BuildManager.EnsureTopLevelFilesCompiled() +421
System.Web.Compilation.BuildManager.CallAppInitializeMethod() +31
System.Web.Hosting.HostingEnvironment.Initialize(ApplicationManager
appManager, IApplicationHost appHost, IConfigMapPathFactory
configMapPathFactory, HostingEnvironmentParameters hostingParameters,
PolicyLevel policyLevel, Exception appDomainCreationException) +691

[HttpException (0x80004005): Could not load file or assembly 'file:///C:\Windows\Microsoft.NET\Framework\v4.0.30319\Temporary

ASP.NET Files\root\bd6e4bde\6cbdacc0\App_global.asax.j5j-uxp-.dll' or
one of its dependencies. The system cannot find the file specified.]
System.Web.HttpRuntime.FirstRequestInit(HttpContext context) +8972180
System.Web.HttpRuntime.EnsureFirstRequestInit(HttpContext context) +97
System.Web.HttpRuntime.ProcessRequestInternal(HttpWorkerRequest wr) +258

So I re install the Vs 2010 also But Same error repeat.

Please Help me to solve this issue.