Facebook – Game Requests appearing in Facebook Notifications area – How to stop it

I would check the following:

• Check that the build of Chrome you are using is stable. If not, use a build that is stable.
• Check if the problem still exists when using a different browser
• Check if the problem still exists when using a different computer (if possible)
• Disable any plugins that you may have installed.

If the problem still exists then according to this Facebook FAQ Article you should report the problem by completing this form (You must be logged in to Facebook to see this form.)

Facebook Help Article for completeness:

My Messages are not loading.

If you are seeing a blank page when accessing your Messages, please follow these steps:

1. Make sure that you are using the most recent version of your internet browser. Click here for information about updating your browser.
2. Try manually refreshing the page a few times (Ctrl+r on PCs; Cmd+r on Macs).
3. Check if this issue is occurring on a different computer as well.

If the problem persists, please submit a report here.

I came here looking for help on this same issue and instead found the answer myself and thought I would share:

• Click on the "Notifications" button / icon at the top left of your profile (third button to the right of the FB logo).

• Hover over the offending notification and an "x" will appear at the top right of the said notification.

• Click on the "x" ("Turn Off") and you will be asked to confirm "Turn off top friend activity notifications"

The End