facebooknotifications
It drives me crazy that I get notifications from people I don't know who have written on the wall of an event that I (along with 3000 other people) was invited to.
I see that you can prevent getting emailed whenever this happens, but is there way to avoid the notification (i.e. the red "globe" with the number lighting up) entirely?
Not a very helpful answer, but this is indeed not possible currently. It's probably for privacy reasons, same as when you're not notified of unfriendings.
Additionally (but surely less of a reason), events are often used large-scale and you'd go crazy if you get an email for each of the 300 people attending.
However, there is a slight chance that http://betterfacebook.net/ is of assistance in your case, but I never tried it myself.
Best Answer
Yep! For Facebook's Notifications on a specific event, here's how to turn them off.
Also related, to disable Email Notifications for events (every event, not just a specific one)