Youtube – Is it possible to create a “smart playlist” (YouTube Mix) from a set of keywords (artists names)

Your method maybe easier than what I am about to tell you but for some reason I can remember this URL.

1. Go to their channel
2. Select "Playlist" on their channel (the tob tabs) you should see the url end (or near the end) with a long list of alphanumeric characters
3. Paste this right before that set of characters http://www.youtube.com/playlist?list=PL
4. This will bring you to the playlist page. You can now select play all or play any of the videos

For example on Skillrex channel we have this playlist

More Monsters & Sprites EP

http://www.youtube.com/user/TheOfficialSkrillex#p/c/1B5CF096FA99B653

and switching out for the PL url

http://youtube.com/playlist?list=PL1B5CF096FA99B653

The playlist is available in the current design (One Channel, which you're referring to as "new design") if the user has featured a "newest video" shelf on their channel page – click the "play all" button.

In the now-new design (Material Design), there is a link to play all videos on the /videos tab of any channel.