Electronic – Reasons for multiple I2C modules in ARM-based MCUs

First, don't use 0x00 and 0x01, those are reserved! Table 3 of the I2C Bus Specification lists the reserved addresses (and reasons why):

Slave addr  R/W        Description
 0000 000    0     General call address
 0000 000    1     START byte
 0000 001    X     CBUS address
 0000 010    X     Reserved for different bus format
 0000 011    X     Reserved for future purposes
 0000 1XX    X     Hs-mode master code
 1111 1XX    1     Device ID
 1111 0XX    X     10-bit slave addressing

You should also steer clear of 0x00 because that has no edge transitions, and might be an error condition (and it's hard to debug).

Other than that, I'd say "Just make it configurable." If you want to be able to plug in a wide variety of sensors, then you can either pay NXP for an address, or give it adjustable addresses. Software modifications should be obvious if you want to distribute the source code. A hardware option to toggle one or two bits of your selected address (solder jumpers on digital pins) is cheap and easy, or a ladder network of resistors with jumpers connected to an A/D pin could give you complete control in the hardware.

I designed[1] something like this using I2C once. (Since I did it for work, I can't post the code.) As long as you have control over all the nodes (they're all MCUs programmed by you), this should work.

Basically, the devices are arranged in a daisy-chain using I2C as normal. In addition to the I2C, you have a point-to-point logic line, using two PIO pins per node. One pin ("upstream sense") is input-only and pulled up, while the other pin ("downstream sense") is output-only, but initially tri-stated (high-Z out) and optionally pulled up. Each node's upstream sense pin is connected to the downstream sense pin of the next chip upstream. The farthest-upstream and farthest-downstream pins are left unconnected. Optionally, each node can have an external FET which connects pull-up resistors to the I2C bus.

On power up, all nodes have their I2C ports as slaves with address 0 or some such (doesn't really matter), drive their downstream sense pins to 0, and wait for a fixed time (depends on how long it takes for all your nodes to power up and initialize). What they're looking to receive is an "all call" (broadcast) message.

Whichever node is farthest upstream will not see its upstream sense pulled low in this time. So it goes first (if pull-ups are FET-controlled, it turns its pull-up on), sets its port as a master, and broadcasts an all-call message identifying itself to the other nodes, including its address (whatever you want to use for the first one) and any other information identifying what it is to the other nodes. Then it waits for a fixed amount of time for another node (should be none, but who knows) to send an all-call message saying that they are in fact at the first address. If it gets such a message, it then repeats its identification, but with the next address. This cycle repeats until it finds an available address. (This pattern allows a node to reset and get its address back without confusing the bus.)

Once it is sure of its address, it sets it in the I2C peripheral and goes to slave mode, to listen for other nodes, and drives its downstream sense line high, which tells the next node downstream to go through the same process to get its address. At this point, it just listens for people trying to claim its address, and records the identification information of the other nodes. (Nodes also listen for other nodes' identification prior to getting a rising edge on upstream sense, building a network table, but they don't have a claimed address yet, so they don't check for collisions. When it comes time to claim an address, it can use the table data to pick a likely unclaimed address.)

After all this, everyone should have unique I2C addresses and be ready to go. Then you just use I2C as normal. (Needless to say, whatever initial address all nodes had could not be used post-configuration.) In our setup, all-call was only used for configuration, and direct addressing was only used for real work. If you want to use all-call after configuration, you'll need to design your all-call message to flag which mode it's in.

There's probably plenty that can be optimized here, but it should give you a start. We used this on a piggyback board for a half-brick power supply, so you could just snap together whatever bricks you needed (we added edge-mating connectors to our boards to carry I2C and the other lines) and then plug into a serial port on any one of the bricks to get voltage, current, and temperature information on all of them. It was pretty sweet and got our student (who did the heavy lifting) an A in senior lab. (Then he ran as fast as he could to grad school across the country...)

[1] By "designed" I mean I wrote up something similar to the text above, the 1% inspiration per Edison. The 99% perspiration was provided by my undergrad student.